Category: 8. Health

  • UN advisor explains cutting back on salt could save millions of lives in India: Here’s how

    UN advisor explains cutting back on salt could save millions of lives in India: Here’s how

    In an interview with HT Lifestyle, Dr Sabine Kapasi – CEO at Enira Consulting, Founder of ROPAN Healthcare, and UN advisor – shared that reducing salt intake is crucial for public health, particularly in India, where excessive salt consumption is linked to approximately 175,000 deaths annually due to high blood pressure-related issues. Also read | Always add extra salt to your meals? Here’s what it actually does to your body over time

    WHO states that excessive sodium intake causes millions of deaths worldwide each year.(Shutterstock)

    The World Health Organization (WHO) recommends a daily sodium intake of less than 2 grams (or 5 grams of salt), but Indians consume over 12 grams of salt daily, more than double the recommended amount. Highlighting this, Dr Kapasi said, “Too much salt is slowly killing people. WHO states that excessive sodium intake causes approximately 1.9 million deaths worldwide each year. The recommended daily intake of sodium is 2 grams, but the average person worldwide consumes more than 4.3 grams.”

    She added, “The situation in India is even worse. A national workshop with Resolve to Save Lives in June this year showed that Indians eat more than 12 grams of salt a day, which is more than twice the recommended amount. This is linked to about 175,000 deaths each year from problems related to high blood pressure.”

    Dr Kapasi further shared that one of the main causes of heart disease, stroke, and kidney problems in the country is high blood pressure: “The cost of treating these conditions is very high, and the economic effects go beyond hospitals. Early deaths and long-term illnesses lower productivity and put more stress on families that are already dealing with rising healthcare costs.”

    Salt hiding in everyday foods

    According to Dr Kapasi, cutting back on salt can be tough because it’s hidden in many foods that don’t even taste salty. “It is hard to cut back on salt because it can be found in foods that most people do not consider salty. Bread, cheese, instant noodles, packaged snacks, canned soups, and even breakfast cereals all have a lot of sodium in them. As more people in cities rely on processed foods, India could make the same mistakes as richer countries, where packaged foods became staples before regulations caught up,” she said.

    Reducing sodium intake is crucial for public health, particularly in countries like India, where excessive salt consumption is linked to numerous deaths. Dr Kapasi shared what we can learn from other countries and how India can benefit.

    She said, “The National Institutes of Health (NIH) says that processed foods make up almost 80 percent of the sodium people in Australia eat. Health officials have made lowering sodium levels in food a top priority because one in three adults already has high blood pressure. The Food and Drug Administration (FDA) has set voluntary goals for food makers in the US to lower the amount of sodium in their products. These examples show that rules and people knowing about them can change how food systems work.”

    She added, “India has an edge in this case. Compared to richer countries, packaged and ultra-processed foods still make up a smaller part of people’s diets. Setting sodium limits early on can prevent people from relying on salty packaged foods.”

    WHO recently said that potassium-enriched salt is a good alternative to regular table salt. It has potassium chloride instead of sodium chloride.(Shutterstock)
    WHO recently said that potassium-enriched salt is a good alternative to regular table salt. It has potassium chloride instead of sodium chloride.(Shutterstock)

    Why potassium-enriched salt is a good option

    Dr Kapasi highlighted that potassium-enriched salt is gaining attention as a healthier alternative to regular table salt – by replacing some sodium chloride with potassium chloride, it reduces sodium intake while increasing potassium consumption, benefiting heart and muscle health.

    She said, “WHO recently said that potassium-enriched salt is a good alternative to regular table salt. It has potassium chloride instead of sodium chloride. This simple change lowers the amount of sodium you eat and raises the amount of potassium, which is important for the health of your heart and muscles. The WHO says that people should get 3.5 grams of potassium every day, but most people do not.”

    “The Lancet published research that says that using potassium-enriched salt widely could save hundreds of thousands of lives each year in countries like India and China. India could see major public health benefits from encouraging its use in homes, schools, and the food industry. Cost and distribution are still problems, but with help from the government and the industry, the product can get to homes of all income levels,” Dr Kapasi added.

    Putting higher rates on foods loaded with sodium and tightening rules on ads that target children could send a clear signal to both companies and consumers.
    Putting higher rates on foods loaded with sodium and tightening rules on ads that target children could send a clear signal to both companies and consumers.

    Why policy should be in charge

    Dr Kapasi explained that implementing nutrition labels on food packages, taxes on high-sodium foods, and stricter advertising regulations can encourage healthier choices. “Individual awareness is helpful, but policy changes are needed to make the system work better. Nutrition labels on the front of packages that are easy to read can help people make choices and force food companies to change their recipes. Countries in Latin America have shown that these kinds of labels make people less likely to buy foods high in sodium,” she said.

    Dr Kapasi added, “Taxes can make a difference too. Putting higher rates on foods loaded with sodium and tightening rules on ads that target children would send a clear signal to both companies and consumers. Food makers may resist, but the savings in healthcare and the lives protected outweigh the short-term opposition.”

    India’s commitment and gaps

    She further shared that India aims to reduce average salt consumption by 30 percent by 2030 — however, progress has been slow due to the lack of a national strategy for reducing salt intake. According to Dr Kapasi, Nutrition Week 2025 (September 1-7) presents an opportunity to push for stronger action and bring policymakers, industry, and healthcare professionals together to address this critical public health issue.

    Dr Kapasi said, “India has promised to cut the average amount of salt people eat by 30 percent by 2030. This is a change from its previous goal of 2025, which was in line with WHO’s global non-communicable disease action plan. Things have not gone smoothly so far, mostly because there is no national strategy for reducing salt intake. The rules are still weak, and not many people know about them.”

    She added that ‘nutrition campaigns are progressing;. “They are reaching more people, and public health advocates are pushing for stronger action. Nutrition Week 2025 is an opportunity to keep salt reduction in focus and bring policymakers, industry, and healthcare professionals to the same table,” Dr Kapasi said.

    A shared responsibility

    According to Dr Kapasi, reducing salt intake is a collective effort that requires government policies, food industry reformulation, healthcare professional guidance, and public awareness. Individuals cannot be the only ones responsible for cutting back on salt.

    She said, “It should be easier to make healthy choices because of government policies. Food companies need to change the way they make their products and market them. Doctors and nurses need to tell their patients about the dangers of eating too much salt. The media and civil society should help raise awareness.”

    “If people do not pay attention, the country could end up with more preventable diseases that hurt the economy and make communities weaker. India’s young population is thought to be an economic strength, but that strength is weakened if high blood pressure and heart disease keep getting worse,” she added.

    Dr Kapasi concluded, “There is no doubt about the evidence that too much salt is killing millions of people around the world and hundreds of thousands in India. Potassium-enriched salt, nutrition labels, taxes on unhealthy products, and stricter advertising rules are all things that can help people eat less. Nutrition Week 2025 should mark a new beginning. One of the cheapest ways to improve public health is to cut down on salt. If put into action with determination, it could save millions of lives, lower healthcare costs, and make life better for generations to come.”

    Note to readers: This article is for informational purposes only and not a substitute for professional medical advice. Always seek the advice of your doctor with any questions about a medical condition.

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  • Larry Ellison Is Spending Billions to Reshape Oxford and His Own Legacy – The Wall Street Journal

    1. Larry Ellison Is Spending Billions to Reshape Oxford and His Own Legacy  The Wall Street Journal
    2. Oxford launches major new AI vaccine research programme with the Ellison Institute of Technology  University of Oxford
    3. Larry Ellison Wants For-Profits to Solve Big Problems. Here’s What That Mindset Overlooks  Inside Philanthropy
    4. Larry Ellison bankrolling £118M AI vaccine research at Oxford University  theregister.com
    5. University Of Oxford: New AI Vaccine Research Program Launched With Ellison Institute Of Technology  Pulse 2.0

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  • Yale neurologist explains women may be at greater risk than men for Alzheimer’s disease for this reason

    Yale neurologist explains women may be at greater risk than men for Alzheimer’s disease for this reason

    Alzheimer’s is a neurodegenerative disease, and the most common form of dementia, accounting for 60-70 percent of cases, according to World Health Organisation. In a November 25, 2024 video shared on Instagram by Yale School of Medicine (YSM), Dr Carolyn Fredericks, a YSM neurologist who specialises in diagnosing and treating patients with cognitive and behavioural concerns, spoke about the potential sex-based differences in brain connectivity that may influence Alzheimer’s disease progression. Also read | Doctor explains how to know if you are at risk of Alzheimer’s disease: ‘There’s 1 test that can help intervene early’

    Understanding the sex-specific differences in Alzheimer’s disease can help tailor prevention and treatment strategies for men and women. (Freepik)

    Alzheimer’s risk in women

    In the video, Dr Fredericks highlighted that women exhibit tighter connections in the posterior default mode network compared to men, a pattern that peaks around age 50 and strikingly resembles scans of individuals with preclinical Alzheimer’s. While this increased connectivity correlates with better memory performance, Dr Fredericks hypothesised it might represent a ‘wear and tear’ effect, making these networks more vulnerable to neurodegeneration later on.

    She said, “The default mode network, which is this network that’s really important for memory and seems to be especially targeted by Alzheimer’s disease, is much more tightly connected in the back parts of it in women than in men. And again, that difference peaks right around age 50. It looks a lot like if you look at scans of people who are amyloid positive, preclinical Alzheimer’s disease, so they have a positive amyloid scan, but they don’t yet have any symptoms. Their scans look very similar. Again, this kind of tightening of the connections in the back part of this network.”

    Dr Fredericks added, “So, it’s very interesting that increased connectivity actually correlates with doing really well in memory tests. So, in a way, it’s an effective it’s an effective tool. It’s working. But it may be sort of like a highway that gets a lot of wear and tear and then becomes more vulnerable down the road compared to one that hasn’t been used quite as much.”

    Does Alzheimer’s affect men and women differently?

    The doctor shared that research aim to understand how these functional network variations in men and women relate to the accumulation of tau protein, a key marker of Alzheimer’s, and contribute to the observed more aggressive disease progression in women.

    Dr Fredericks said, “So, that’s something that we’re trying to unpack. We want to look at the relationship between functional networks and that pathological protein tangle that I mentioned and try to understand how women and men might vary in the composition and properties of these networks and how that might contribute to more aggressive progression of tau in women.”

    Alzheimer’s disease is a growing public health concern, affecting millions worldwide. From staying physically active to having a brain-nourishing diet, click here to learn about a few habits that can help keep Alzheimer’s at bay.

    Note to readers: This report is based on user-generated content from social media. HT.com has not independently verified the claims and does not endorse them.

    This article is for informational purposes only and not a substitute for professional medical advice.

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  • Diagnostic Accuracy of Screening Tests for Diabetic Peripheral Neuropathy Among Outpatient Attendees of Follow-Up Care for Diabetes in Central India

    Diagnostic Accuracy of Screening Tests for Diabetic Peripheral Neuropathy Among Outpatient Attendees of Follow-Up Care for Diabetes in Central India


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  • Cardiologist shares 5 easy things people need to do in their 20s, 30s to protect heart health: Eat spinach, take stairs

    Cardiologist shares 5 easy things people need to do in their 20s, 30s to protect heart health: Eat spinach, take stairs

    Serious conditions like heart attacks were initially thought to affect older adults who had crossed middle age. But lately, heart attack scares are showing up more in young adults, as young as their 20s and 30s. Dr M Srinivasa Rao, regional clinical director and senior interventional cardiologist at CARE Hospitals, Banjara Hills in Hyderabad, also warned, revealing that many young adults are ending up in the hospital with very serious cardiac issues.

    Fit and sporty individuals can suffer heart attacks or sudden cardiac arrests due to various reasons. Here is what to know. (Freepik)

    ALSO READ: Cardiologist shares 5 compelling reasons to eat more home-cooked meals instead of ordering food online

    Poor lifestyle is the biggest contributor to this surge in heart issues, as Dr Rao told HT Lifestyle that there are many lifestyle factors, along with genetic predisposition, responsible for increasing the risks of cardiac issues in young adults. He elaborated, “Long work hours, stress, irregular sleep, fast food habits, undiagnosed high blood pressure, elevated cholesterol, diabetes, and a family history of heart disease. Even everyday exposure to pollution or occasional smoking can quietly damage arteries.”

    Another common misconception is that poor health will also affect one’s appearance. However, this is not always the case; one may appear fine from the outside, but the damage has already started inside. Dr Rao warned, “A young adult might look fit on the outside, but early plaque can already be forming inside their blood vessels.”

    This is why heart health cannot be pushed down the list of urgent priorities. People in their 20s and 30s are often more focused on skincare routines, treating early fine lines with retinol (as one should), but it’s also vital to pay attention to things that were earlier thought to be a concern in midlife- like cardiac health.

    Right from the beginning, lifestyle needs to be changed, embracing healthier habits not just once in a while, but as a regular part of life. One of the essentials for keeping the heart healthy is staying active, even in small ways like taking stairs instead of the lift. He called it, “Consider exercise as giving your heart a daily workout rather than waiting for the weekend gym session.”

    Dr Rao shared five tips young adults should follow to protect their hearts:

    1. Watch what you are eating

    Include more green vegetables in your diet.(Shutterstock)
    Include more green vegetables in your diet.(Shutterstock)
    • Vegetables like spinach, broccoli, and carrots, fruits such as berries and oranges, whole grains like oats and brown rice, and healthy fats from nuts, seeds, olive oil, or avocado should make up most meals.
    • Fast food, sugary drinks, processed snacks, and excess salt should be occasional treats rather than daily staples.

    2. 150 minutes of exercise every week

    Be active and include daily movements through activities like brisk walking.(Shutterstock)
    Be active and include daily movements through activities like brisk walking.(Shutterstock)
    • Aim for at least 150 minutes a week of brisk walking, cycling, or swimming, and include two strength-training sessions.
    • Short bursts of activity during the day, taking the stairs, walking to a colleague’s desk, or a quick evening jog, can all add up.

    ALSO READ: Take the stairs over lift: Study reveals just 3 minutes of daily movement can reduce heart attack and stroke risk

    3. Check health numbers regularly

    The health numbers reveal the health issue even before symptoms show up, so early detection allows you to take action before serious problems arise. (Shutterstock)
    The health numbers reveal the health issue even before symptoms show up, so early detection allows you to take action before serious problems arise. (Shutterstock)
    • Blood pressure, cholesterol, blood sugar, body weight and waist circumference often reveal hidden risks before symptoms appear.
    • A young adult might feel fine, yet their arteries could be under stress.

    4. Manage stress

    Young adults may be under a lot of stress at work, making stress management a must to protect heart. (Shutterstock)
    Young adults may be under a lot of stress at work, making stress management a must to protect heart. (Shutterstock)
    • Chronic stress raises blood pressure and inflammation in arteries.
    • Techniques like yoga, short breathing exercises, or even a 10-minute phone-free walk during the day can help.
    • Consider stress management as important as any diet or exercise.

    5. Say no to smoking and drinking

    From smoking, vaping, to drinking- they all put your heart health at risk. Young adults often are seen smoking or drinking, either from stress or at parties. (Freepik)
    From smoking, vaping, to drinking- they all put your heart health at risk. Young adults often are seen smoking or drinking, either from stress or at parties. (Freepik)
    • Heavy drinking strains the heart and can trigger dangerous rhythms.
    • Tobacco accelerates artery damage and increases clotting risk.
    • Social binge drinking can put susceptible young adults at risk.

    It is vital to change negative habits and embrace healthier ones as heart attack is not waiting until middle age to hit, so don’t treat early adulthood like 20s and 30s as your lively years to ‘enjoy’ and openly neglect health.

    Note to readers: This article is for informational purposes only and not a substitute for professional medical advice. Always seek the advice of your doctor with any questions about a medical condition.

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  • 7 silent signs of kidney problems that people commonly overlook

    7 silent signs of kidney problems that people commonly overlook





    7 silent signs of kidney problems that people commonly overlook













































































    06 Sep, 2025




    Harpreet Kour













    Constant tiredness may sometimes be noticed as an early sign of kidney problems that people overlook.













    Swelling in feet, ankles, or hands could signal kidney problems, yet many ignore it as routine fatigue.













    Dry or itchy skin may appear when kidney problems are quietly affecting the body.













    Back pain or discomfort near the lower side is sometimes linked to kidney problems.













    Changes in urination patterns may indicate kidney problems that need attention but often go unnoticed.













    Puffiness around the eyes could be a hidden sign of kidney problems that people do not take seriously.













    Trouble focusing or brain fog can be a subtle sign of kidney problems that most people miss.















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  • WHO adds GLP-1 weight loss drugs to list of the world's essential medicines for the first time – Quartz

    1. WHO adds GLP-1 weight loss drugs to list of the world’s essential medicines for the first time  Quartz
    2. WHO adds weight-loss, diabetes drugs to essential medicines list  Al Jazeera
    3. WHO updates list of essential medicines to include key cancer, diabetes treatments  World Health Organization (WHO)
    4. MSF responds to inclusion of rapid-acting insulin analogues and GLP-1s to WHO Essential Medicines List  MSF Access Campaign
    5. WHO Backs Weight-loss Drugs, Urges Cheap Generics  Barron’s

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  • Anaesthesia Challenges in Patients With Chronic Kidney Disease: A Clinical Approach From Internal Medicine

    Anaesthesia Challenges in Patients With Chronic Kidney Disease: A Clinical Approach From Internal Medicine


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  • Can potassium supplements help lower the risk of heart failure?

    Can potassium supplements help lower the risk of heart failure?

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    Maintaining high blood potassium levels, for instance, by taking supplements, may help lower heart failure risk. Image credit: Viktoriya Skorikova/Getty Images
    • A new trial investigating high-normal serum potassium levels for people at high risk of ventricular arrhythmias delivered promising results.
    • Compared to a control group, people with these elevated potassium levels fared better over the approximately 3 years of the trial.
    • Too little potassium is bad for the heart, and so is too much. The trial suggested a new sweet spot for at-risk heart patients.

    The study, conducted at three sites in Denmark, was called the POTCAST trial, for “Targeted Potassium Levels to Decrease Arrhythmia Burden in High-Risk Patients with Cardiovascular Diseases.”

    The trial tracked for 3.3 years the cardiovascular health of participants maintaining high-normal potassium levels compared to a control group whose potassium levels were not being treated.

    This was done by measuring the incidence of specific cardiovascular events: sustained ventricular tachycardia, necessary life-saving ICD therapy, unplanned hospitalization of greater than 24 hours for arrhythmia or heart failure, or death from any cause.

    By the end of the trial, just 22.7% of study participants with high-normal potassium levels had experienced one of these events, compared to 29.2% of individuals in the untreated group.

    Specifically, just 15.3% of high-normal potassium individuals experienced a ventricular tachycardia event or required ICD therapy, compared to 20.3% of the normal potassium participants, while for the untreated group, 10.7% required hospitalization for arrhythmia, compared to 6.7% of those in the high-normal group.

    There were no significant differences between the groups regarding the incidence of hospitalization for hyperkalemia (overly high potassium levels) or hypokalemia (overly low potassium levels).

    The target potassium level for the high-normal group in the study was 4.5-5.0 mmol/L (millimoles per liter). The average potassium level of participants at the baseline was 4.01 mmol/L.

    The trial aimed to identify an increased level of potassium that was high enough to aid heart function without being so high as to cause damage.

    Members of the high-normal group received mineralocorticoid receptor antagonists and/or potassium supplements, as well as dietary guidance to increase their serum potassium to the target level over a period of 85 days.

    They had also reduced or completely discontinued any current use of potassium-losing diuretics.

    “Normal serum potassium levels are critical to maintaining the electrical stability of the heart,” Roy Ziegelstein, MD, of DynaMed at EBSCO Clinical Decisions, not involved in this study, told Medical News Today. “In fact, either low or high potassium levels can cause unstable heart rhythms.”

    Jayne Morgan, MD, cardiologist and the Vice President of Medical Affairs for Hello Heart, likewise not involved in this study, explained that:

    “This is because cardiac action potentials depend on potassium gradients between the inside and outside of the heart muscle cells. This controls repolarization.”

    The fact that participants in the trial all had cardioverter defibrillators made them especially sensitive to the electrical effects of potassium levels, said Ziegelstein, “since their electrical system of their heart is already more vulnerable than those without a similar history.”

    The designers of this trial clearly hoped to identify a “good sweet spot” for potassium levels, as suggested by panelist Theresa McDonagh, MD, of King’s College London during the trial results’ presentation at the European Society of Cardiology Congress.

    “Low levels also can create a risk of arrhythmias, just as high levels can,” said Morgan. “This includes superventricular tachycardia, torsades de pointes, and even cardiac arrest in severe cases. Levels below 2.5 mmol/L carry a severe risk level, with levels between 2.5-2.9 mmol/L carrying a moderate risk level.”

    Too-high potassium levels pose perhaps the most profound danger, she said.

    “The most serious risk is the very thing that is trying to be avoided by increasing the potassium range, which are arrhythmias,” cautioned Morgan, “including ventricular fibrillation, and asystole [cessation of heart function].”

    Finally, she added, “In addition to ECG changes, nerve and/or muscle function can be impacted, including diaphragmatic weakness.”

    “This,” said Ziegelstein, “is something we must consider when recommending potassium supplements to patients, or when treating patients with other medications that may increase serum potassium levels.”

    Morgan termed the findings of the trial as “interesting,” and noted that they mirror the results of other studies.

    However, she said, “it is worth noting that the mortality benefit is not realized until year 4, and that the active arm included more patients with a greater time since ICD therapy by 22%,” implying they may have more completely recovered from previous events than the control group.

    “The comparison of human ancestral diets that were richer in potassium and lower in sodium is confounding, as the life expectancy was frequently less than 45 years ancestrally,” was another concern for Morgan.

    She noticed as well that: “There were also more hospitalizations for electrolyte issues (presumably hyperkalemia), signaling the importance of very close monitoring. There is a narrow therapeutic window. As such, the treatment can also be the detriment outside of the window.”

    Ziegelstein, too, expressed concern regarding the difficulty of tightly monitoring patients at higher potassium levels, noting that, “in this study, participants had blood tests performed every other week to make sure that their potassium was in the desired range and neither too high nor too low — this is often very difficult to do in routine clinical practice.”

    The bottom line is that people with cardiovascular disease who may be interested in investigating the possibility of upping their potassium levels should make sure to consult their cardiologist first.

    Do not increase your potassium levels yourself without proper medical guidance, given the potential risk involved, the experts MNT spoke to cautioned.

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  • LSD shows promise for reducing anxiety, shows drugmaker’s study

    LSD shows promise for reducing anxiety, shows drugmaker’s study

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    LSD reduced symptoms of anxiety in a mid-stage recent study, paving the way for additional testing and possible medical approval of a psychedelic drug that has been banned in the US for more than half a century.

    The results from drugmaker Mindmed tested several doses of LSD in patients with moderate-to-severe generalised anxiety disorder, with the benefits lasting as long as three months. The company plans to conduct follow-up studies to confirm the results and then apply for Food and Drug Administration approval.

    Beginning in the 1950s, researchers published a flurry of papers exploring LSD’s therapeutic uses, though most of them don’t meet modern standards.

    “I see this paper as a clear step in the direction of reviving that old research, applying our modern standards and determining what are the real costs and benefits of these compounds,” said Frederick Barrett, who directs Johns Hopkins University’s psychedelic centre and was not involved in the research.

    Psychedelic research is rebounding

    Psychedelics are in the midst of a popular and scientific comeback, with conferences, documentaries, books and medical journals exploring their potential for conditions like depression, anxiety and post-traumatic stress disorder.

    The FDA has designated psilocybin, MDMA and now LSD as potential “breakthrough” therapies based on early results.

    Still, the drugs have not had a glide path to the market.

    Last year, the FDA rejected MDMA — also known as ecstasy — as a treatment for PTSD, citing flawed study methods, potential research bias and other issues.

    The new LSD study, published by the Journal of the American Medical Association, addresses some of those problems.

    MDMA, like many other psychedelics, was tested in combination with hours of talk therapy by trained health professionals. That approach proved problematic for FDA reviewers, who said it was difficult to separate the benefits of the drug from those of therapy.

    The LSD study took a simpler approach: Patients got a single dose of LSD — under professional supervision, but without therapy — and then were followed for about three months.

    The paper does not detail how patients were prepared for the experience or what sort of follow-up they received, which is crucial to understanding the research, Barrett noted.

    “In many cases, people can have such powerful, subjective experiences that they may need to talk to a therapist to help them make sense of it,” he said.

    Anxiety eased, but questions remain

    For the study, researchers measured anxiety symptoms in nearly 200 patients who randomly received one of four doses of LSD or a placebo. The main aim was to find the optimal dose of the drug, which can cause intense visual hallucinations and occasionally feelings of panic or paranoia.

    At four weeks, patients receiving the two highest doses had significantly lower anxiety scores than those who received placebo or lower doses. After 12 weeks, 65 per cent of patients taking the most effective LSD dose — 100 micrograms — continued to show benefits and nearly 50 per cent were deemed to be in remission. The most common side effects included hallucinations, nausea and headaches.

    Patients who got dummy pills also improved — a common phenomenon in psychedelic and psychiatric studies — but their changes were less than half the size those getting the real drug.

    The research was not immune to problems seen in similar studies.

    Most patients were able to correctly guess whether they’d received LSD or a dummy pill, undercutting the “blinded” approach that’s considered critical to objectively establishing the benefits of a new medicine. In addition, a significant portion of patients in both the placebo and treatment groups dropped out early, narrowing the final data set.

    It also wasn’t clear how long patients might continue to benefit.

    Mindmed is conducting two large, late-stage trials that will track patients over a longer period of time and, if successful, be submitted for FDA approval.

    “It’s possible that some people may need retreatment,” said Dr. Maurizio Fava of Mass General Brigham Hospital, the study’s lead author and an adviser to Mindmed. “How many retreatments, we don’t know yet, but the long-lasting effect is quite significant”.

    Interest from the Trump administration

    Health Secretary Robert F. Kennedy Jr. and other administration officials have expressed interest in psychedelic therapy, suggesting it could receive fast-track review for veterans and others suffering psychological wounds.

    Generalised anxiety disorder is among the most common mental disorders, affecting nearly 3 per cent of US adults, according to the National Institutes of Health. Current treatments include psychotherapy, antidepressants and anti-anxiety drugs like benzodiazepines.

    The possibility of using LSD as a medical treatment isn’t new.

    In the 1950s and 1960s, more than 1,000 papers were published documenting LSD’s use in treating alcohol addiction, depression and other conditions. But a federal backlash was in full swing by the late 1960s, when psychedelics became linked to counterculture figures like Timothy Leary, the ex-Harvard professor who famously promoted the drugs as a means to “turn on, tune in and drop out”.

    A 1970 law classifying LSD and other psychedelics as Schedule 1 drugs — without any medical use and high potential for abuse — essentially halted U.S. research.

    When a handful of nonprofits began reassessing the drugs in the 1980s and 1990s, they focused on lesser-known hallucinogens like MDMA and psilocybin, the main ingredient in magic mushrooms, to avoid the historic controversies surrounding LSD.

    “LSD was right there in front of everybody, but Mindmed is the first company that actually decided to evaluate it,” Fava said.

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