Category: 3. Business

  • Clarification of methodology for Turkey domestic long steel assessments

    Clarification of methodology for Turkey domestic long steel assessments

    The assessments are for MB-STE-0784 steel reinforcing bar (rebar) domestic, exw Turkey and MB-STE-0785 steel wire rod (mesh quality) domestic, exw Turkey.

    Previously, both assessments stated that an 18% value-added tax (VAT) was included in the assessed price. Fastmarkets wishes to clarify the specifications to show the correct figure, which is 20%, as dictated by Turkish tax rules.

    Turkey changed its VAT rate from 18% to 20% in July 2023. The specifications of affected prices were not updated at the time, but prices have been assessed in line with the VAT change.

    The clarified specifications are:

    MB-STE-0784 Steel reinforcing bar (rebar) domestic, exw Turkey, lira/tonne
    Quality: Diameter 12-32mm
    Quantity: Minimum 100 tonnes
    Location: Ex-works
    Timing: Up to 6 weeks
    Unit: TRY/tonne including 20% VAT
    Payment terms: LC, Bank transfer, cash upon order, deferred payment
    Publication: Weekly. Thursday, 2-3pm London time

    MB-STE-0785 Steel wire rod (mesh quality) domestic, exw Turkey, lira/tonne
    Quality: Standard diameter 5.5-32mm
    Quantity: Standard 100 tonnes
    Location: Ex-works
    Timing: Prompt to 6 weeks
    Unit: TRY/tonne including 20% VAT
    Payment terms: LC, Bank transfer, cash upon order, deferred payment
    Publication: Weekly. Thursday, 2-3pm London time

    You can find the updated methodology for ferrous products here: https://www.fastmarkets.com/methodology/.

    To see all Fastmarkets pricing methodology and specification documents, go to the Fastmarkets methodology page.

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  • Eastern Airways on brink of collapse putting with jobs at risk

    Eastern Airways on brink of collapse putting with jobs at risk

    UK regional airline Eastern Airways is on the brink of collapse, putting hundreds of jobs at risk.

    On Monday it filed a notice of intention to appoint an administrator, and several regional flights were cancelled including between between Teesside and Aberdeen.

    Eastern Airways operates across the UK, Ireland and Europe, and has run services supported by the Scottish government for people in the northernmost point of mainland UK.

    Eastern Airways and The UK Civil Aviation Authority (CAA) have been approached for comment.

    A notice to appoint administrators is a formal step that gives the business up to 10 days of legal protection from creditors while it explores rescue options, restructures, or prepares for insolvency proceedings.

    Airport flight departure boards showed Eastern Airways flights had been cancelled, including a 0700 flight from Newquay to London Gatwick, 1815 flight from Teesside to Aberdeen, 1430 from Aberdeen to Wick and 1645 from Aberdeen to Teesside.

    Eastern Airways is one of the UK’s last remaining regional airlines.

    It has been an operator in the oil and gas industry, flying between UK cities with a significant presence in the sector such as Aberdeen, Humberside, Teesside and Wick.

    The airline faced financial challenges following the pandemic, due in part to falling passenger numbers.

    Launched in 1997, Eastern Airways is based at Humberside Airport in North Lincolnshire. The airline also operates out of East Midlands, Jersey, Manchester, Newcastle, Newquay and Southampton, as well as Esbjerg in Denmark.

    It has run a crucial weekday service between Wick John O’Groats Airport and Aberdeen, which is seen as vital for people living in the most northerly point on mainland UK, which was supported by a Public Service Obligation (PSO) by the Scottish Government.

    Eastern Airways initially built up its network of scheduled services around the North Sea offshore industry with flights up the east coast of England to Aberdeen.

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  • How John Williamson transformed the LME

    How John Williamson transformed the LME

    Key takeaways:

    • LME’s transformation under John Williamson: From navigating the 2022 nickel crisis to modernizing systems and governance, Williamson has steered the LME toward renewed trust and market confidence
    • Driving modernization and sustainability: Williamson’s tenure emphasizes electronic pricing, enhanced transparency, and sustainability initiatives like the Dubai-based CPAL for greener metals
    • Strengthened global partnerships: Closer ties with HKEX have fueled expansion, governance reforms, and strategic growth, positioning the LME for a dynamic future

    The nickel crisis of 2022 had tested its systems, its governance and its reputation. Three years later, Williamson says that the LME is “no longer the ugly duckling” – a reference to the fable he uses to describe its transformation – but is now an exchange regaining confidence, focus and trust.

    “It brings you back to the story of the ugly duckling,” Williamson told Fastmarkets in an interview on Friday October 24. “When I arrived as chairman, things were rather bleak, and I sensed pretty quickly that we had very good people at the LME and that, like the duckling, with the right support, encouragement and sense of belief, great things could be achieved.”

    Since then, he has presided over an intense period of reform: rebuilding governance, strengthening market surveillance and modernizing systems, all while pushing forward with new initiatives on sustainability and digital trading. “If my legacy was that I had at least helped that duckling gain some more confidence, I’d be happy,” he said.

    Rebuilding after crisis

    Williamson did not seek the chairmanship. He was a long-serving board member of Hong Kong Exchanges & Clearing (HKEX) – the Hong Kong-based owner of the LME – and was invited to join the LME board in 2021 soon after retiring from HKEX. When his predecessor stepped down after the nickel market turmoil, he was asked to lead the exchange through its most testing period in decades.

    In his view, the nickel crisis proved to be a turning point.

    “Much has been learned from the nickel event, not least in terms of our surveillance of what’s happening in the broader market, and the need for us to have access to as much information as possible, on both the over-the-counter [OTC] and exchange business,” he said. “I think we’re in a better place there.”

    The crisis, he said, helped to drive overdue change within the industry, with members becoming more receptive to reforms once they saw the need for greater transparency and oversight. The exchange introduced daily price limits, enhanced data collection on OTC positions, and other measures that helped to facilitate a more comprehensive and proactive approach to risk monitoring.

    “If we’re looking for evidence that the changes we’ve been making are beneficial to the market, we can already see some of that,” he said.

    Modernizing the market

    Williamson’s tenure has been defined by a push to modernize – from electronic pricing and enhanced liquidity programs to IT system upgrades and new product development. It is a strategy that he defines as “evolution, not revolution.”

    “It’s about ensuring that the LME remains the premier venue for trading industrial metals,” he said. “We must continue to nurture and build on the trust that exists in the LME in terms of participants’ desire to use it for reference pricing, and we also must move with the times in terms of being efficient and effective in the way we operate.”

    The exchange has rolled out electronic closing prices and market structure reforms intended to increase transparency and attract a wider pool of participants.

    “We understand the concerns that some market participants have,” he said. “But if I look, for example, at the changes we made to the closing prices, and making those electronic, what you see is a fairly significant increase in volume. And even those who were opposed to us taking those steps have by and large come round to them.”

    Dubai and the CPAL

    Beyond technology, Williamson is also driving a longer-term strategy concerning sustainability and global reach. One of his key priorities is the creation of the Commodity Pricing and Analysis Ltd (CPAL) operation in Dubai, a major step in developing a premium market for greener metal.

    “Another important area, which is more business development than reform, is to continue to pursue the sustainability agenda. Setting up the CPAL operation will be very helpful on that part of the journey,” he said, noting it will operate as an independent pricing administrator.

    Williamson sees the project as part of the LME’s role to help the industry to recognize and reward lower-carbon production.

    “If you make the criteria too demanding, there’ll be no trading,” he said. “So we probably have to start at a reasonable point and then – over time, when we get the right engagement, the right volume – ratchet-up the criteria. Because if the whole idea is to encourage more sustainable green mining, you want to raise the bar over time, in line with broader expectations and policy measures.”

    The initiative mirrors the earlier success of LMEpassport, a traceability tool that once faced skepticism but is now widely used. “When we started to look at LMEpassport, there were a lot of detractors saying it was not really our business to go down that path. But thank goodness we did,” he said.

    HKEX partnership

    According to Williamson, the LME’s relationship with parent company HKEX – once perceived as distant – has become closer and, strategically, more aligned.

    “The engagement with Hong Kong is stronger, not in a micro-managing way, but the business development opportunities are better understood,” he said. “We have, I’d say, an even stronger relationship with Hong Kong. And how does that manifest itself? When we need help on something, we’re not starting from scratch.”

    That partnership has already borne fruit, with rapid expansion of warehouses in Hong Kong (where 12 have opened this year) and the planned establishment of the Dubai office, among other initiatives.

    Williamson also credits HKEX’s support with accelerating governance and cultural reform at the LME. “We’ve strengthened the LME board and management team. There’s much more ambition within the exchange as well as enhanced execution capabilities,” he said. “It’s been interesting to me to observe how the culture has changed. We’ve got a more proactive culture across the organization now.”

    Personal roots

    Despite the LME’s global scope, Williamson’s own story is deeply grounded in personal experience and people skills – something he traces back to his early years working in his father’s newsagent shop in Edinburgh, Scotland.

    “I worked there from the age of eight until I was 21,” he said. “I learned so much in that time about people – you learned to read people pretty quickly because our shop was on the border of the then less-attractive part of Edinburgh.”

    That grounding, he believes, shaped his approach to business and leadership. “Although I’m an accountant and I’ve been dealing with numbers all my life, I’m much happier dealing with people and people issues and people challenges,” he said.

    After earning a degree in accounting and computer science from Edinburgh’s Heriot-Watt University, he joined stockbroking firm Wood Mackenzie and started as a partnership tax assistant in Edinburgh. He gained the mentorship of a senior partner, who later encouraged him to move to London around the time of the so-called Big Bang in banking; they remain close friends some 42 years later.

    Williamson moved to Hong Kong in 1994 after Wood Mackenzie was acquired by UK bank NatWest, acting as the bank’s eyes and ears in a 50:50 investment bank joint venture with Wheelock, a major local conglomerate. His role focused on building the right team and establishing operations across the Asia region.

    In 1998, he then joined Morgan Stanley in Hong Kong to help expand its business in Asia, gaining valuable experience, not least in navigating the differences between US and UK banking cultures.

    In 2007, he was recruited by Robert Miller, co-founder of DFS Group, to be chief financial officer of Search Group, Miller’s private family office and asset management firm. Later, in 2012, Williamson was also appointed chief executive officer of SAIL Advisors, the group’s fund of hedge funds business.

    Meantime, in 2008, he had been approached to join the HKEX board. It proved an extraordinary time, with the global financial crisis unfolding and Hong Kong facing a series of challenges, from market turmoil to public health crises such as SARS and bird flu. Despite the turbulence, it was a fascinating period that saw HKEX begin to expand its international reach.

    Williamson was part of the board subcommittee that looked into acquiring the LME in 2012. “That was my first proper introduction to the world of metals,” he said.

    Looking ahead

    Reflecting on three years as chairman, Williamson said that his focus was still to ensure that the LME continues to evolve – cautiously, but decisively.

    “We’re very, very careful not to interfere with the structure of the LME’s core contracts,” he said. “But if we do not adapt to the changing requirements of the broader market, we’re in more danger of being left behind.”

    For all the challenges, he is optimistic and energized.

    “We’ve made remarkable progress over the past few years,” he said. “There’s no room for complacency, but I genuinely believe that the LME is poised to reach its full potential. We’re certainly heading in the right direction.”

    Want to hear more from about the London Metal Exchange? Listen to the exchange’s CEO, Matthew Chamberlain, in an episode of the Fast Forward podcast with Andrea Hotter below.

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  • Strengthening ChatGPT’s responses in sensitive conversations – OpenAI

    1. Strengthening ChatGPT’s responses in sensitive conversations  OpenAI
    2. OpenAI prioritised user engagement over suicide prevention, lawsuit claims  Financial Times
    3. How ChatGPT Encourages Teens to Engage in Dangerous Behavior  Inside Higher Ed
    4. 10-21-25 open ai rolling out parental controls for ai chatbot chatgpt  radioplusinfo.com
    5. OpenAI Weakened ChatGPT’s Self-Harm Guardrails in Lead-Up to Teen’s Death, Lawsuit Says  Gizmodo

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  • AI in Health Care and Biotechnology: Promise, Progress, and Challenges – Foley & Lardner LLP

    1. AI in Health Care and Biotechnology: Promise, Progress, and Challenges  Foley & Lardner LLP
    2. AI in Biotechnology Market to Reach $11.4 Billion by 2030  Yahoo Finance
    3. From wild fungi to faster drug discovery  Drug Target Review
    4. AI giants Nvidia, Microsoft and Google are making critical moves in pharma R&D  PharmaVoice
    5. Artificial Intelligence in Drug Discovery Market 2025-2032: Trends, Growth Drivers & Global Forecast  PharmiWeb.com

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    Reference #18.d9b31402.1761583326.6ad9acdc

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  • Some ‘correction cushions’ just in case all this market euphoria is misplaced

    Some ‘correction cushions’ just in case all this market euphoria is misplaced

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  • Hyundai Motor Group and Toray Group Strengthen Ties to Develop Advanced Materials for Future Mobility

    • Hyundai Motor Group and Toray Group to develop advanced materials for future mobility, including high-performance vehicles and special-purpose mobility
    • Hyundai Motor Group will carry out vehicle-level design, performance evaluation and suitability assessments of advanced materials and components
    • Toray Group will focus on developing intermediate materials and molded products based on its carbon fiber technologies
    • The two companies will collaborate across the entire value chain in the field of high-performance composites, from R&D to production and commercialization


    SEOUL, October 27, 2025
    – Hyundai Motor Group and Toray Industries, Inc. (Toray Group) signed a Strategic Joint Development Agreement to collaborate on advanced materials and components innovation, aiming to set new standards in future mobility.

    The signing ceremony took place on October 24 at Hyundai Motor Group’s headquarters in Seoul, Korea. Key attendees included Heung-soo Kim, Executive Vice President and Head of Global Strategy Office at Hyundai Motor Group and Miki Terada, General Manager of Advanced Composites Division at Toray Group.

    “This agreement marks an important milestone in our partnership, as it represents the first tangible outcome of our strategic collaboration initiated last year,” said EVP Kim. “By clearly defining our focus areas and combining our respective strengths, we will work closely together across the entire process—from R&D to production and commercialization—in the field of advanced composite materials, enhancing our ability to respond to market demands.”

    Miki Terada, General Manager of Advanced Composites Division at Toray Group, also commented that “The Joint Development Agreement marks a significant step forward in advancing the partnership established in the previous year. Leveraging Toray’s unique material technologies and extensive expertise, we will collaborate closely with Hyundai Motor Group to create innovative composite solutions essential for next-generation mobility. From R&D to production and commercialization, we will work in close coordination to enhance our competitiveness in the global market.”

    Building on the strategic cooperation agreement signed in April 2024, the two companies have continued to work together to develop high-performance composite materials, such as carbon fiber-reinforced plastic (CFRP), to enhance safety and performance in mobility.

    Since then, the two companies have identified projects that maximize synergy through close collaboration and have outlined concrete plans for joint development by leveraging their respective strengths.

    The newly signed agreement represents a major step forward in their collaboration, accelerating the development of advanced materials and components for future mobility, including high-performance vehicles as well as special-purpose mobility such as lunar exploration rovers and robots.

    Hyundai Motor Group aims to accelerate innovation in future mobility and create new market opportunities through close collaboration with Toray Group across the entire value chain—from technology development to production and commercialization—in the field of high-performance composite materials.

    As part of this effort, Hyundai Motor Group will carry out vehicle-level design, suitability assessments and performance evaluations of advanced materials and components through its Materials Research & Engineering Center, which is responsible for developing and validating new body materials.

    The development and production of carbon fiber composites will be carried out by Toray Group’s global subsidiaries: Toray Advanced Materials Korea, Toray Advanced Composites in the Netherlands and Euro Advanced Carbon Fiber Composites in Germany. These entities focus on developing intermediate materials and molded products based on Toray Group’s carbon fiber technology.

     

    – End –

    About Toray
    Toray is a leading technology and advanced materials innovator. We have contributed to social progress since our foundation in 1926 by creating new values. We help the world to overcome new challenges by supplying fibers and textiles, resins and films, carbon fiber composite materials, and other high value-added products. Our 306 subsidiaries and affiliates worldwide employ almost 48,000 people.

    About Hyundai Motor Group
    Hyundai Motor Group is a global enterprise that has created a value chain based on mobility, steel, and construction, as well as logistics, finance, IT, and service. With about 250,000 employees worldwide, the Group’s mobility brands include Hyundai, Kia, and Genesis. Armed with creative thinking, cooperative communication, and the will to take on any challenges, we strive to create a better future for all.

    More information about Hyundai Motor Group can be found at: http://www.hyundaimotorgroup.com or Newsroom: Media Hub by Hyundai, Kia Global Media Center (kianewscenter.com), Genesis Newsroom

    Contact:
    Kyeongjin Kim
    Global PR Strategy & Planning / Hyundai Motor Group
    kyeongjin.kim@hyundai.com

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  • Hyundai Motor Group and Toray Group Strengthen Ties to Develop Advanced Materials for Future Mobility

    • Hyundai Motor Group and Toray Group to develop advanced materials for future mobility, including high-performance vehicles and special-purpose mobility
    • Hyundai Motor Group will carry out vehicle-level design, performance evaluation and suitability assessments of advanced materials and components
    • Toray Group will focus on developing intermediate materials and molded products based on its carbon fiber technologies
    • The two companies will collaborate across the entire value chain in the field of high-performance composites, from R&D to production and commercialization


    SEOUL, October 27, 2025
    – Hyundai Motor Group and Toray Industries, Inc. (Toray Group) signed a Strategic Joint Development Agreement to collaborate on advanced materials and components innovation, aiming to set new standards in future mobility.

    The signing ceremony took place on October 24 at Hyundai Motor Group’s headquarters in Seoul, Korea. Key attendees included Heung-soo Kim, Executive Vice President and Head of Global Strategy Office at Hyundai Motor Group and Miki Terada, General Manager of Advanced Composites Division at Toray Group.

    “This agreement marks an important milestone in our partnership, as it represents the first tangible outcome of our strategic collaboration initiated last year,” said EVP Kim. “By clearly defining our focus areas and combining our respective strengths, we will work closely together across the entire process—from R&D to production and commercialization—in the field of advanced composite materials, enhancing our ability to respond to market demands.”

    Miki Terada, General Manager of Advanced Composites Division at Toray Group, also commented that “The Joint Development Agreement marks a significant step forward in advancing the partnership established in the previous year. Leveraging Toray’s unique material technologies and extensive expertise, we will collaborate closely with Hyundai Motor Group to create innovative composite solutions essential for next-generation mobility. From R&D to production and commercialization, we will work in close coordination to enhance our competitiveness in the global market.”

    Building on the strategic cooperation agreement signed in April 2024, the two companies have continued to work together to develop high-performance composite materials, such as carbon fiber-reinforced plastic (CFRP), to enhance safety and performance in mobility.

    Since then, the two companies have identified projects that maximize synergy through close collaboration and have outlined concrete plans for joint development by leveraging their respective strengths.

    The newly signed agreement represents a major step forward in their collaboration, accelerating the development of advanced materials and components for future mobility, including high-performance vehicles as well as special-purpose mobility such as lunar exploration rovers and robots.

    Hyundai Motor Group aims to accelerate innovation in future mobility and create new market opportunities through close collaboration with Toray Group across the entire value chain—from technology development to production and commercialization—in the field of high-performance composite materials.

    As part of this effort, Hyundai Motor Group will carry out vehicle-level design, suitability assessments and performance evaluations of advanced materials and components through its Materials Research & Engineering Center, which is responsible for developing and validating new body materials.

    The development and production of carbon fiber composites will be carried out by Toray Group’s global subsidiaries: Toray Advanced Materials Korea, Toray Advanced Composites in the Netherlands and Euro Advanced Carbon Fiber Composites in Germany. These entities focus on developing intermediate materials and molded products based on Toray Group’s carbon fiber technology.

     

    – End –

    About Toray
    Toray is a leading technology and advanced materials innovator. We have contributed to social progress since our foundation in 1926 by creating new values. We help the world to overcome new challenges by supplying fibers and textiles, resins and films, carbon fiber composite materials, and other high value-added products. Our 306 subsidiaries and affiliates worldwide employ almost 48,000 people.

    About Hyundai Motor Group
    Hyundai Motor Group is a global enterprise that has created a value chain based on mobility, steel, and construction, as well as logistics, finance, IT, and service. With about 250,000 employees worldwide, the Group’s mobility brands include Hyundai, Kia, and Genesis. Armed with creative thinking, cooperative communication, and the will to take on any challenges, we strive to create a better future for all.

    More information about Hyundai Motor Group can be found at: http://www.hyundaimotorgroup.com or Newsroom: Media Hub by Hyundai, Kia Global Media Center (kianewscenter.com), Genesis Newsroom

    Contact:
    Kyeongjin Kim
    Global PR Strategy & Planning / Hyundai Motor Group
    kyeongjin.kim@hyundai.com

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  • IDWeek 2025: novel phage AP-SA02 leads to earlier resolution of S. aureus bacteremia

    IDWeek 2025: novel phage AP-SA02 leads to earlier resolution of S. aureus bacteremia

    At IDWeek 2025, held on 19–22 October, Dr Loren Miller from Harbor-UCLA Medical Center/Lundquist Institute presented efficacy and safety data from a Phase Ib/IIa randomised, placebo-controlled trial investigating Armata Pharmaceuticals’ intravenous bacteriophage cocktail, AP-SA02, in adult patients with bacteremia caused by Staphylococcus aureus.

    Bacteriophages, or phages, are viruses that can selectively target and kill bacteria. They work by infecting specifically targeted bacteria with phage DNA. This allows the phage to replicate inside of the host cell, produce phage offspring, and then lyse the bacterial cell to release the new phages. Phages are particularly advantageous anti-infectives as they are novel therapeutics, can target antibiotic-resistant bacteria, can be used as monotherapy or combination therapy, and do not cause microbiome disruption in patients.

    S. aureus is a commensal bacterium and part of the natural human microbiome in approximately 30% of people. Conversely, S. aureus can lead to serious infections, particularly in those with chronic health conditions, in intensive care units (ICUs), or with weakened immune systems. Staphylococcus aureus bacteremia (SAB) can lead to serious bloodstream infections, including cellulitis, sepsis, and endocarditis. The World Health Organization (WHO) categorised methicillin-resistant S. aureus (MRSA) as a high-priority pathogen in the 2024 WHO Bacterial Priority Pathogens List.

    The Phase IIa portion of the diSArm trial (NCT05184764) included 42 patients who were 18 years of age or older and had been hospitalized and diagnosed with a positive blood culture for S. aureus. These patients were randomised into two groups: those receiving intravenous AP-SA02 at a dose of 2×10¹⁰ plaque forming units (PFU) or 5×10¹⁰ PFU every six hours for five days, in addition to intravenous standard of care (SOC) best available antibiotic therapy (BAT) for 14–56 days, or those in the placebo group receiving SOC BAT for 14–56 days. Test-of-cure (TOC) screenings were performed seven days after the end of AP-SA02 (Day 12), seven days after the end of BAT (Day 18–60), and 28 days after the end of BAT (Day 39–81).

    The site of infections in the patients in the study included septic joint, cellulitis, osteomyelitis, pneumonia, sepsis, and endocarditis; 19 of the patients tested positive for MRSA. The BAT antibiotics included cefazolin, vancomycin, oxacillin/nafcillin, daptomycin, cefepime, and ceftriaxone; some patients received more than one antibiotic.

    At all TOC screenings, the clinical response in patients receiving AP-SA02 plus BAT was higher than in patients who had received the placebo plus BAT, including in patients with MRSA and methicillin-susceptible S. aureus (MSSA). On average, the AP-SA02 plus BAT–treated patients observed an initial resolution of their SAB infection in 2.7 days, compared to 9.3 days in the placebo plus BAT–treated group. Additionally, the AP-SA02 plus BAT–treated patients were discharged from the hospital after approximately 11.7 days and had a mean C-reactive protein level of 50.2mg/l on Day 12, compared to 19.2 days and 97.3mg/l, respectively, in the placebo plus BAT group.

    Overall, AP-SA02 was found to be generally safe and well tolerated. Adverse events (AEs) were observed in 66% of patients who received the AP-SA02 plus BAT therapy, and treatment-emergent AEs (TEAEs) were observed in 59% of these patients. Only one patient was reported as having study drug–related TEAEs. One patient death was reported in the AP-SA02 plus BAT group, but this was found to be unrelated to infection, the study drug, or the BAT antibiotic.

    The results of the Phase IIa trial support AP-SA02’s advancement into Phase III development. Armata Pharmaceuticals plans to initiate this pivotal study in 2026. The clinical success of AP-SA02 highlights its potential to fulfil a critical need for SAB patients.



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