In silico validation of 16S rRNA gene metataxonomic analysis
Vaginal mock community and database selection
To select the most suitable database for this dataset, a comparison of different 16S rRNA gene taxonomic databases was conducted using an in…
Category: 6. Health
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Anaplastic large cell lymphoma in the penis: a case report and review of literature | Journal of Medical Case Reports
Anaplastic large cell lymphoma (ALCL), a distinct form of non-Hodgkin lymphoma, was initially documented by Stein et al. in 1985 [10]. The World Health Organization’s 2016 classification system categorizes ALCL into four types on the basis of…
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Nutritional management of metabolic disorders in neonates and infants in Saudi Arabia: consensus recommendations | Orphanet Journal of Rare Diseases
General principles of nutritional management
Early diagnosis and management of IEM are essential. Newborn screening programs for IEM enable early detection, before the development of symptoms, and can improve quality of life and life expectancy is…
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Press Release Service: ChristianaCare Gene Editing Institute Achieves CRISPR Breakthrough That Reverses Chemotherapy Resistance in Lung Cancer
Nov. 17, 2025
Study in Molecular Therapy Oncology shows gene editing restores drug sensitivity by targeting NRF2, with potential across multiple tumor types
WILMINGTON, Del.–(BUSINESS WIRE)–In a major step forward for cancer care, researchers at…
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Malaria outbreak prediction at the sub-district level in Zambia using remote sensing satellite data | Malaria Journal
The study site was the Macha Mission Hospital catchment area, a subarea of Choma District located in Southern Province, Zambia (Fig. 1). The area is one of low seasonal malaria transmission predominantly via the malaria vector Anopheles…
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Associations between six cumulative insulin resistance-related indices and incident stroke in individuals with different glucose regulation statuses: a national cohort study in China | Lipids in Health and Disease
Stroke represents a major public health burden in China. Accordingly, developing scalable methods for early stroke prediction is imperative. The present results constitute the first comprehensive evidence elucidating the associations and…
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Unraveling gut microbiome interferences in cancer immunotherapy: a meta-analysis of diverse drug effects | BMC Cancer
Study selection
A total of 3373 studies were retrieved from PubMed, Embase, Cochrane Library, and Web of Science, including 12 references from other publications. After removing 1,026 duplicates, 2055 studies were excluded based on title and…
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A novel serum-based steroid-protein panels for differentiating ovarian cancer from non-malignant adnexal masses | Cancer Cell International
Description of the cohort
Between December 2021 and February 2025, a total of 103 participants were recruited, and preoperative morning serum samples were collected (Fig. 1). Among them, 47 (45.6%) had ovarian cancer, including 42 (89.4%) with…
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Early lactate and its metabolism for predicting persistent renal failure in patients with acute pancreatitis: a retrospective observational study | BMC Gastroenterology
This study aimed to investigate the predictive value of the changes of lactate and its metabolic indicator (LDH) within 24 h in patients with acute pancreatitis for persistent renal failure. The results showed that different combinations of…
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