Introduction
Depression, also known as depressive disorder, is a highly prevalent mental disorder.1 It can be significant and persistent. Some patients may self-harm or exhibit suicidal behavior, and may even have psychotic symptoms such as…

Depression, also known as depressive disorder, is a highly prevalent mental disorder.1 It can be significant and persistent. Some patients may self-harm or exhibit suicidal behavior, and may even have psychotic symptoms such as…

Homocysteine (Hcy) is a sulfur-containing amino acid that cannot be synthesized de novo in humans and is produced exclusively through the metabolism methionine (Met).1 Metabolically, Hcy can not only be remethylated to Met but also…

Low back pain (LBP) refers to pain occurring in the area from the twelfth rib down to the iliac crests and is one of the most common causes of loss of working capacity, constituting a significant global health issue.1 The causes of…

People with Type 2 diabetes (T2D) and an elevated risk for cardiovascular disease (CVD) who took low-dose aspirin were less likely to experience a major cardiovascular event, including heart attack, stroke or death, than people…

Peptic ulcer disease (PUD), characterized by mucosal breaks in the stomach or duodenum, is a significant cause of morbidity worldwide. In the adult population, the etiology is predominantly linked to Helicobacter pylori (H. pylori)…

Lung cancer remains the leading cause of cancer-related mortality worldwide, accounting for approximately 1.8 million deaths annually according to global cancer statistics.1 Surgical resection remains the cornerstone of…

The medicines regulator will aim to take a more flexible licensing approach for the research and manufacture of rare disease therapies in the UK.

The Medicines and Healthcare products Regulatory Agency (MHRA) is aiming to make sweeping changes to…

Despite being single-celled organisms that are invisible to the naked eye, bacteria have profoundly shaped the world we live in, and they continue to do so. Bacteria had an essential role in the evolution of complex cells, are the basis of…

Surgical site infections (SSIs) are defined as infections that develop at or near the surgical incision after surgery. They can affect the skin, subcutaneous tissue, deeper soft tissues, or any implanted material [1]. The causative pathogens…
A study that reviewed health records for tens of thousands of adults with chronic insomnia found that people who took prescribed melatonin for more than a year had a higher chance of heart failure over five years compared with people who were…