Category: 3. Business

  • Gene editing therapy shows success against severe sickle cell disease – Medical Xpress

    1. Gene editing therapy shows success against severe sickle cell disease  Medical Xpress
    2. Base-Editing Gene Therapy Shows Promise in Sickle Cell Disease  MedPage Today
    3. Beam Therapeutics Announces Publication of BEACON Phase 1/2 Data for risto-cel in Patients with Sickle Cell Disease (SCD) in The New England Journal of Medicine  The Manila Times
    4. Beam Therapeutics publishes sickle cell therapy trial data  investing.com
    5. In 31 sickle cell patients, Beam saw no severe pain crises after risto-cel  Stock Titan

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  • TransUnion Completes Acquisition of the Mobile Division of RealNetworks

    TransUnion Completes Acquisition of the Mobile Division of RealNetworks

    TransUnion remains committed to fostering innovation within the telecommunications sector and enabling secure, trusted interactions between businesses and consumers,” said Mohamed Abdelsadek, Chief Global Solutions Officer, TransUnion. “As the digital landscape rapidly evolves, we are strengthening our solutions for businesses seeking reliable, scalable messaging.”

    “For more than 20 years, our mobile team has developed innovative products that enable trusted communications worldwide,” said Rob Glaser, Chairman and Chief Executive Officer, RealNetworks Group. “We are grateful to our many customers and partners for their support. I also want to deeply thank the Real Mobile team members who are now joining the TransUnion team.”

    TransUnion’s Trusted Call Solutions have improved outbound calling by increasing contact rates, enriching customer experience with additional context, blocking fraudulent calls, and confirming call authentication. With the addition of RealNetworks’ cutting-edge telecom platform, TransUnion plans to offer a broader suite of voice, messaging and analytics tools that help businesses more effectively communicate with their customers.

    “We expect integrating RealNetworks’ mobile capabilities with Trusted Call Solutions will allow TransUnion to deliver a comprehensive, identity-anchored omnichannel engagement platform,” added James Garvert, SVP of Communications Solutions, TransUnion. “We look forward to providing more seamless, secure communications across both voice and messaging channels to help consumers and businesses connect with greater confidence.”

    The terms of the transaction have not been disclosed. The transaction was funded with existing cash-on-hand and is not expected to have a material impact on leverage, liquidity or TransUnion’s 2026 operating results.

    About TransUnion (NYSE: TRU)

    TransUnion is a global information and insights company with over 13,000 associates operating in more than 30 countries. We make trust possible by ensuring each person is reliably represented in the marketplace. We do this with a Tru™ picture of each person: an actionable view of consumers, stewarded with care. Through our acquisitions and technology investments we have developed innovative solutions that extend beyond our strong foundation in core credit into areas such as marketing, fraud, risk and advanced analytics. As a result, consumers and businesses can transact with confidence and achieve great things. We call this Information for Good® — and it leads to economic opportunity, great experiences and personal empowerment for millions of people around the world. http://www.transunion.com/business

    About RealNetworks

    Building on 30+ years of digital media innovation, RealNetworks creates AI-powered products that enhance and secure our daily lives. Real’s portfolio includes: SAFR®, a unified computer vision platform for enterprise security and access control; GameHouse®, a mobile games business delivering great games for women; and RealPlayer®, the iconic media player reimagined with AI. Learn more at www.realnetworks.com

    TransUnion Forward-Looking Statements

     This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. These statements are based on the current beliefs and expectations of TransUnion’s management and are subject to significant risks and uncertainties, many of which are beyond our control. Actual results may differ materially from those described in the forward-looking statements. Any statements made in this press release that are not statements of historical fact, including statements about our beliefs and expectations, are forward-looking statements. Forward-looking statements include information concerning anticipated benefits of the transaction, including strategic, business and anticipated benefits to our results of operations and descriptions of our business plans, prospects and strategies.

    Factors that could cause actual results to differ materially from those described in the forward-looking statements include: failure to realize the synergies and other benefits expected from the acquisition of the mobile division of RealNetworks the possibility that the acquisition, including the integration of the mobile division of RealNetworks, may be more costly to complete than anticipated; business disruption following the acquisition closing; potential business uncertainty, including adverse reactions or changes to business relationships resulting from the completion of the acquisition; the effects of pending and future legislation and regulatory actions and reforms; macroeconomic and industry trends and adverse developments in the telecommunications software and services, debt, consumer credit and financial services markets and other macroeconomic factors beyond TransUnion’s control; risks related to TransUnion’s indebtedness, including our ability to make timely payments on principal and interest and our ability to satisfy covenants in the agreements governing our indebtedness; and other one-time events and other factors, including those found in our Annual Report on Form 10-K for the year ended December 31, 2025, and any subsequent Annual Report on Form 10-K, Quarterly Report on Form 10-Q or Current Report on Form 8-K, which are filed with the Securities and Exchange Commission and are available on TransUnion’s website. You should evaluate all forward-looking statements made in this press release in the context of these risks and uncertainties. The forward-looking statements contained in this press release speak only as of the date of this press release. We undertake no obligation to publicly release the result of any revisions to these forward-looking statements to reflect the impact of events or circumstances that may arise after the date of this press release.

    ';

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  • Stock market today: Live updates

    Stock market today: Live updates

    Traders work on the floor of the New York Stock Exchange.

    NYSE

    Stocks rose on Wednesday, while oil prices declined to start the month, as hope grew that an end to the U.S.-Iran war was on the horizon.

    The S&P 500 was up 0.8%, and the Nasdaq Composite gained 1.1%. The Dow Jones Industrial Average added 269 points, or 0.6%.

    President Donald Trump said in a post on Truth Social Wednesday morning that Iran’s president has asked the U.S. for a ceasefire. However, the U.S. will consider the offer when the Strait of Hormuz is “open, free, and clear,” Trump added, writing that “until then, we are blasting Iran into oblivion or, as they say, back to the Stone Ages!!!”

    This comes after the president told reporters at the White House late Tuesday that he expects the U.S. military forces will leave Iran in “two or three weeks.”

    Oil prices eased following that comment. They were last trading around $100, with West Texas Intermediate futures settling down 1.24% to close at $100.12 per barrel and Brent crude futures settling 2.7% lower at $101.16 a barrel.

    “The market is kind of just sniffing out that there’s probably some type of resolution in the next couple of weeks,” said Patrick Ryan, chief investment strategist and head of multi-asset solutions at Madison Investments.

    Optimism around a potential end to the war sent stocks soaring on Tuesday, the final trading day of March.

    The moves came after an unconfirmed report said that Iranian President Masoud Pezeshkian was open to ending the war with guarantees. He made similar remarks earlier in March, saying in an X post that the “only way to end this war … is recognizing Iran’s legitimate rights, payment of reparations, and firm int’l guarantees against future aggression.”

    However, the market may not be out of the woods yet. According to Ryan, unless there’s “some type of all-clear announcement,” trading should “remain volatile” in the short term.

    Investors will get more clues on the path forward for the U.S.-Iran war Wednesday at 9 p.m. ET, with Trump set to deliver an address “to the nation to provide an important update.”

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  • How The Nebius Group (NBIS) Investment Story Is Shifting With New AI Deals And Valuation Adjustments

    How The Nebius Group (NBIS) Investment Story Is Shifting With New AI Deals And Valuation Adjustments

    Find your next quality investment with Simply Wall St’s easy and powerful screener, trusted by over 7 million individual investors worldwide.

    Nebius Group’s fair value estimate has shifted from about US$159.29 to roughly US$165.85, reflecting updated assumptions in the latest analyst models. That change sits against a backdrop of busy Street research, with views being refreshed after new AI infrastructure contracts, financing plans, and earnings details. As you read on, you will see how this evolving narrative is taking shape and how to track it over time.

    Analyst Price Targets don’t always capture the full story. Head over to our Company Report to find new ways to value Nebius Group.

    • Citi, Compass Point, BofA, Freedom Capital and Northland have all started or reiterated positive views on Nebius, focusing on its role as an AI infrastructure and AI cloud platform provider.

    • DA Davidson and BWS Financial both lifted Nebius price targets to US$200, citing large long term AI compute contracts with Meta worth about US$27b in aggregate across recent deals.

    • Northland raised its target from US$211 to US$232 and refers to Nebius as a top pick, pointing to an updated 2026 ARR estimate of US$5.4b after the latest Q4 report.

    • Several firms highlight Nebius as a leading or emerging AI hyperscaler and neocloud player, with Citi and others referencing potential share gains in AI workloads and capacity additions.

    • Morgan Stanley initiated with a more neutral stance, signaling that not all firms see the current risk and reward skew in the same way as the more enthusiastic brokers.

    • Northland notes that the period to secure debt tied to the US$17b Microsoft contract has raised some investor concern, with funding timelines and service level obligations viewed as key execution factors.

    Do your thoughts align with the Bull or Bear Analysts? Perhaps you think there’s more to the story. Head to the Simply Wall St Community to discover more perspectives!

    NasdaqGS:NBIS 1-Year Stock Price Chart

    We’ve flagged 3 risks for Nebius Group. See which could impact your investment.

    • Fair value estimate adjusted from about US$159.29 to roughly US$165.85.

    • Modeled revenue growth rate adjusted from 212.28% to about 206.36%.

    • Net profit margin assumption adjusted from 3.48% to around 11.39%.

    • Future P/E multiple assumption adjusted from about 161x to roughly 37x.

    • Discount rate adjusted from 8.42% to about 8.71%.

    Narratives link a company’s story to a financial forecast and fair value, tying contracts, competition, and funding back to specific numbers. They update as new deals, regulations, and execution milestones come through, so you can see how the thesis is evolving in real time.

    Head over to the Simply Wall St Community and follow the Narrative on Nebius Group to stay up to date on:

    • How AI infrastructure demand, including large contracts with customers such as Meta and Microsoft, feeds into long term capacity buildouts and recurring revenue expectations.

    • The impact of heavy GPU and data center investment, global expansion into regions such as the U.S., Europe, Israel and Finland, and partnerships with firms like Nvidia, Cloudflare and Shopify on Nebius Group’s business profile.

    • Risks from intense competition, open source adoption, regulatory and environmental requirements, customer concentration and Nebius Group’s relatively limited global brand recognition.

    This article by Simply Wall St is general in nature. We provide commentary based on historical data and analyst forecasts only using an unbiased methodology and our articles are not intended to be financial advice. It does not constitute a recommendation to buy or sell any stock, and does not take account of your objectives, or your financial situation. We aim to bring you long-term focused analysis driven by fundamental data. Note that our analysis may not factor in the latest price-sensitive company announcements or qualitative material. Simply Wall St has no position in any stocks mentioned.

    Companies discussed in this article include NBIS.

    Have feedback on this article? Concerned about the content? Get in touch with us directly. Alternatively, email editorial-team@simplywallst.com

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  • SLB and Rockwell Automation Complete Sensia Joint Venture Dissolution

    SLB and Rockwell Automation Complete Sensia Joint Venture Dissolution

    HOUSTON, April 1, 2026 — SLB (NYSE: SLB) and Rockwell Automation, Inc. (NYSE: ROK) today announced the completion of the previously announced dissolution of their Sensia joint venture.

    SLB has assumed ownership of the Lift Control, Measurement, Digital Solutions, and Edge Application businesses, while Rockwell Automation will take full ownership of the Process Automation & vMonitor products business. Both SLB and Rockwell Automation remain committed to ensuring a smooth transition and sustaining service excellence for customers worldwide.

    With full ownership, SLB will further advance its portfolio in lift control, measurement, and digital solutions, enhancing value and operational insights for energy sector customers. The company’s enhanced offerings, powered by industry-leading digital and measurement technologies, are designed to support clients’ efficiency, reliability, and productivity goals.

    About SLB

    SLB (NYSE: SLB) is a global technology company that has driven energy innovation for 100 years. With a global footprint in more than 100 countries and employees representing almost twice as many nationalities, we work each day on innovating oil and gas, delivering digital at scale, decarbonizing industries, and developing and scaling new energy systems that accelerate the energy transition. Find out more at slb.com.

    Media

    Josh Byerly – SVP of Global Communications
    Moira Duff – Director of External Communications
    SLB
    Tel: +1 (713) 375-3407
    Email: media@slb.com

    Investors

    James R. McDonald – SVP of Investor Relations & Industry Affairs
    Joy V. Domingo – Director of Investor Relations
    SLB
    Tel: +1 (713) 375-3535
    Email: investor-relations@slb.com

     

    Cautionary Statement Regarding Forward-Looking Statements:
    This press release contains “forward-looking statements” within the meaning of the U.S. federal securities laws — that is, statements about the future, not about past events. Such statements often contain words such as “expect,” “may,” “can,” “estimate,” “intend,” “anticipate,” “will,” “potential,” “projected” and other similar words. Forward-looking statements address matters that are, to varying degrees, uncertain, such as forecasts or expectations regarding the deployment of, or anticipated benefits of, SLB’s new technologies and partnerships; statements about goals, plans and projections with respect to sustainability and environmental matters; forecasts or expectations regarding energy transition and global climate change; and improvements in operating procedures and technology. These statements are subject to risks and uncertainties, including, but not limited to, the inability to achieve net-negative carbon emissions goals; the inability to recognize intended benefits of SLB’s strategies, initiatives or partnerships; legislative and regulatory initiatives addressing environmental concerns, including initiatives addressing the impact of global climate change; the timing or receipt of regulatory approvals and permits; and other risks and uncertainties detailed in SLB’s most recent Forms 10-K, 10-Q and 8-K filed with or furnished to the U.S. Securities and Exchange Commission. If one or more of these or other risks or uncertainties materialize (or the consequences of such a development changes), or should underlying assumptions prove incorrect, actual outcomes may vary materially from those reflected in our forward-looking statements. The forward-looking statements speak only as of the date of this press release, and SLB disclaims any intention or obligation to update publicly or revise such statements, whether as a result of new information, future events or otherwise.


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  • LKQ Academy and Valeo sign a strategic agreement to train the ECP network on the latest technologies

    LKQ Academy and Valeo sign a strategic agreement to train the ECP network on the latest technologies

    Valeo Group | 1 Apr, 2026
    | 6 min

    April 1, 2026 – Paris, France – In a context of deep transformation in the automotive market, LKQ Academy, LKQ Europe’s automotive training provider, and Valeo, a global leader in automotive technology, announce a structuring partnership aimed at supporting mechanical repairers and body shops in developing their competency on the most recent technologies.

    Faced with the rise of electrified vehicles, ADAS systems, and the increasing complexity of diagnostics, training becomes a decisive lever for performance and competitiveness for workshops.

    Lee Chapman, Head of Support and LKQ Academy at LKQ Euro Car Parts, said “Workshops are being asked to keep pace with increasingly complex vehicle technologies, from electrification to ADAS, while still maintaining productivity and profitability day to day. That is why training has such an important role to play.

    Through LKQ Academy, our focus is on giving technicians practical skills, confidence and support that they can take straight back into the workshop. By partnering with Valeo Tech Academy, we’re combining leading technical expertise with accessible, high-quality training that helps our customers reduce diagnostic time, work safely on newer vehicle systems and build long-term capability for the future.”

    Marlene Carrias-Iked, Vice President of Strategic Marketing and Digital Services at Valeo, declares “This partnership between Valeo Tech Academy and LKQ Academy marks a key milestone in our common ambition: to sustainably raise the competence level of aftermarket professionals, by combining Valeo’s technological leadership and the expertise of the ECP network, a major player in the aftermarket in the UK. Together, we are offering a high added-value training program, serving the performance and transformation of the sector. Through our innovative pedagogical approach and industry-recognized IMI certification, we ensure technicians are fully equipped to master the challenges of tomorrow’s mobility.”

    A common commitment to strengthen field expertise

    This collaboration capitalizes on Valeo’s worldwide leadership position in both electrification, as evidenced by its technology being present in one out of every three hybrid and electric vehicles globally, and in ADAS, with its systems integrated into one out of every three new cars worldwide.

    Together, Valeo and LKQ Academy offer a technical training program dedicated to new powertrains, electrification, and driver assistance systems, covering all makes and vehicle architectures.

    Launched at the end of 2024, Valeo Tech Academy provides brand-agnostic training, covering all automotive systems and brands, not just Valeo products, to ensure a comprehensive learning experience across the entire automotive landscape. The Valeo Tech Academy training program is IMI-certified, ensuring recognized, high-quality standards aligned with the expectations of the automotive industry and reinforcing the credibility of technicians’ skills development.

    An innovative training approach focused on workshop performance

    These programs aim to reduce diagnostic time and strengthen intervention capabilities across all vehicle types, helping professionals better manage complex system interactions and sustainably improve workshop efficiency and profitability.

    The program begins with short, interactive digital modules, effectively preparing participants for in-person sessions.

    Then, the in-person sessions propose innovative educational solutions, concrete case studies of workshop entries, and the handling of tools identical to those used by professionals. Deployed regionally, closer to the repairers, they rely on a unique and innovative pedagogical approach based on advanced simulators, enabling:

    • visualization of internal components and system interactions
    • practice on more than 150 real-life fault scenarios
    • training across all vehicle brands and architectures
    • use of the same diagnostic tools as in the workshop, in a safe environment

    This approach allows technicians to accelerate their understanding, gain confidence, and develop operational skills faster than traditional vehicle-based training.

    Finally, to strengthen the practical application, a follow-up webinar is organized a few weeks after returning to the workshop, offering learners the opportunity to share their experiences and issues with their peers and their trainer.

    The collaboration between Valeo and LKQ Academy was initiated in February 2026. The enthusiastic response from the first participating technicians highlights the immediate value of the program and its promising future.

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  • Hydrogen Europe

    Hydrogen Europe